ADVANCES IN PHARMACOSOMES: A COMPREHENSIVE REVIEW OF FORMULATION STRATEGIES, CHARACTERIZATION TECHNIQUES, AND THERAPEUTIC APPLICATIONS IN DRUG DELIVERY SYSTEMS

Abstract

Pharmacosomes represent an innovative approach in drug delivery systems, wherein drug molecules are conjugated with lipid vesicles to enhance their solubility, stability, and bioavailability. This review encompasses the recent advancements and emerging trends in the field of pharmacosomes, a dynamic and evolving drug delivery platform. Pharmacosomes, characterized by the conjugation of drug molecules with lipid vesicles, have garnered substantial attention for their potential to address challenges associated with drug solubility and bioavailability.This novel drug delivery system offers several advantages, including improved therapeutic efficacy, reduced toxicity, and targeted delivery to particular tissues or cells. This comprehensive review synthesizes the latest research findings, focusing on the formulation strategies, characterization techniques, and applications of pharmacosomes. The review also explores the impact of pharmacosomes on drug delivery, emphasizing their role in improving therapeutic outcomes, minimizing toxicity, and facilitating targeted delivery. Pharmacosomes have received a lot of interest in the pharmaceutical sector because of their ability to overcome problems connected with poorly water-soluble medicines. This abstract gives an outline of the concept, formulation, and uses of pharmacosomes in drug delivery, highlighting their role in enhancing drug performance and optimizing therapeutic outcomes. By summarizing the current state of knowledge, this review provides valuable insights into the future directions and potential innovations in pharmacosome-based drug delivery systems.

KEYWORDS: Pharmacosomes, drug delivery, lipid vesicles, solubility, stability, bioavailability, therapeutic efficacy, toxicity, targeted delivery, poorly water-soluble drugs.